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Rapid genotyping of low density lipoprotein receptor knockout mice using a polymerase chain reaction technique
A Gaw1, F P Mancini, S Ishibashi
1Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas 75235, USA.
Laboratory Animals
|October 1, 1995
Abstract:
A new method for the rapid genotyping of low density lipoprotein receptor knockout mice is described. This method using a polymerase chain reaction (PCR) technique may be performed on small tissue biopsies, and represents a significant advantage in time over conventional genotyping by Southern blot analyses.