AH17, a new non-polyenic antifungal antibiotic produced by a strain of Spirillospora
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Updated: Oct 19, 2026

Live Imaging of Antifungal Activity by Human Primary Neutrophils and Monocytes in Response to A. fumigatus
Published on: April 19, 2017
1Laboratoire de Microbiologie, Université des Sciences et de la Technologie Houari-Boumediène, Alger-Gare, Algeria.
Abstract:
An antibiotic (AH17) was produced by Spirillospora strain 719. This substance was obtained only from the broth filtrate after precipitation with acetic acid followed by extraction with n-butanol. Its purification was carried out by thin layer chromatography on silica gel followed by HPLC procedures. It showed activity against Gram-positive and Gram-negative bacteria and fungi. The spectroscopic and chemical properties were examined and indicated that AH17 was a quinone. It seems that this is a new antibiotic from Spirillospora.
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Fungal Group Zygomycota
Fungal Phylum Microsporidia
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