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Should an echocardiographic scan be done routinely for infants of diabetic mothers?
M Vural1, L Leke, H Mahomedaly
12nd Service of Pediatrics, Picardie Jules Verne University Faculty of Medicine, Amiens, France.
Insights
Asymmetrical septal hypertrophy (ASH) is common in infants of diabetic mothers, but often missed. Echocardiography screening for ASH in these neonates is recommended due to its association with cardiac insufficiency.
Area of Science:
- Neonatal cardiology
- Pediatric echocardiography
- Diabetology
Background:
- Infants of diabetic mothers (IDMs) are at risk for various cardiac conditions.
- Asymmetrical septal hypertrophy (ASH) is a frequent pathology in IDMs but not routinely screened for.
- Early detection of ASH is crucial for managing potential complications.
Purpose of the Study:
- To determine the incidence of ASH in hospitalized IDMs.
- To investigate the correlation between ASH and corporeal index in IDMs.
- To assess the association between ASH and cardiac insufficiency in IDMs.
Main Methods:
- Retrospective echocardiographic examination of 56 neonates born to diabetic mothers.
- Comparison of corporeal index and cardiac insufficiency rates between IDMs with and without ASH.
- Statistical analysis to determine significance (p < 0.05).
Main Results:
- ASH was diagnosed in 17 out of 56 (30%) hospitalized IDMs.
- IDMs with ASH exhibited a significantly greater corporeal index compared to those without ASH (p < 0.05).
- Cardiac insufficiency was more prevalent in IDMs with ASH (24%) than in those without ASH (3%) (p < 0.05).
Conclusions:
- ASH is a significant and frequent finding in infants of diabetic mothers.
- Routine echocardiographic screening for ASH in IDMs is warranted.
- ASH in IDMs is associated with increased risk of cardiac insufficiency.
Abstract:
Several cardiologic pathologies are seen in infants of diabetic mothers (IDMs). Though asymmetrical septal hypertrophy (ASH) is a frequent pathology in IDMs, it is not routinely searched for with an echocardiographic scan. We have performed an echocardiographic examination for all IDMs (56 neonates) hospitalized between January 1987 and December 1992 in our neonatology and neonatal reanimation units. Of 56 patients, the diagnosis of 17 cases of ASH 930%) was made. The group with ASH (17 neonates) had a greater corporeal index than the group without ASH (39 neonates) (p < 0.05). Four of the 17 IDMs (24%) with ASH and one of the 39 IDMs (3%) without ASH presented with a cardiac insufficiency (p < 0.05). ASH is a pathology which should be searched for routinely IDMs.