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Updated: Aug 10, 2026

FISH for Pre-implantation Genetic Diagnosis
Published on: February 23, 2011
Prenatal diagnosis of genital anomalies
D P Smith1, R E Felker, H N Noe
1Department of Urology, University of Tennessee, Memphis 38163, USA.
Objectives:
This is a report of five cases of abnormal fetal genitalia detected by routine prenatal ultrasound.
Methods:
Retrospective review was conducted to identify all cases of abnormal fetal genitalia identified by routine obstetrical ultrasound at our institution in which postpartum follow-up was available.
Results:
Five cases of prenatal sonographically diagnosed abnormal fetal genitalia were confirmed postnatally. The abnormalities include ambiguous genitalia, severe hypospadias with unilateral cryptorchidism, megalourethra, and concealed penis. In all cases, other anomalies were discovered during the prenatal ultrasound.
Conclusions:
Prenatal ultrasound may detect a variety of abnormalities of the fetal genitalia.
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