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Characterization of the hog cholera virus 5' terminus
K Katayama1, C Kurihara, S Fukushi
1Basic Research Division, BioMedical Laboratories, Saitama, Japan.
Virus Genes
|January 1, 1995
Abstract:
Hog cholera virus (HoCV) 5' terminus of the ALD and GPE(-) strains were analyzed by using rapid amplification of cDNA end method (5'RACE). An additional nine nucleotides were found at the 5' termini of genomic RNA in the ALD and GPE(-) strains of HoCV. These nine nucleotides were also conserved in BVDV and were suggested to form a hairpin structure at the 5' terminus by computer-assisted analysis. It seems possible that the secondary structure and/or the 5' terminus sequence has a significant role in the HoCV virus genome.