Related Experiment Video
Updated: Aug 12, 2026

13:25
Transient Transduction of the Strobilated Forms of Echinococcus granulosus
Published on: September 16, 2022
Imported echinococcosis in southern California
S M Donovan1, N Mickiewicz, R D Meyer
1Department of Medicine, UCLA Medical Center, UCLA School of Medicine, USA.
The American Journal of Tropical Medicine and Hygiene
|December 1, 1995
Summary
Infection with Echinococcus granulosus is common in immigrants from the Middle East. A high index of suspicion is needed for this parasitic infection, even without clear risk factors.
Area of Science:
- Medical Parasitology
- Infectious Diseases
- Epidemiology
Background:
- Echinococcus granulosus infection (echinococcosis) is a parasitic disease.
- It is endemic in many parts of the world, particularly in sheep-raising areas.
- Diagnosis can be challenging due to varied clinical presentations.
Purpose of the Study:
- To investigate the characteristics of Echinococcus granulosus infections in a Los Angeles County population.
- To identify risk factors and clinical presentations in affected patients.
- To emphasize the importance of early diagnosis in specific demographic groups.
Main Methods:
- Retrospective chart review of 28 patients diagnosed with Echinococcus granulosus infection between 1981 and 1990.
- Analysis of patient demographics, country of origin, and exposure history.
- Review of cyst locations and diagnostic methods (serology and/or biopsy).
Main Results:
- Eighty-nine percent of patients were foreign-born, with 68% immigrating from the Middle East or Central Asia.
- Epidemiologic risk factors like rural residence or dog exposure were reported by only half of the immigrants.
- Cysts were found in the liver, lung, soft tissue, and other organs, with multiple cysts being common.
Conclusions:
- Immigrants from the Middle East represent a significant risk group for imported Echinococcus granulosus infections in the US.
- The absence of typical epidemiologic risk factors and varied clinical presentations necessitate a high index of suspicion.
- Clinicians should consider echinococcosis in patients with cystic masses, especially in this demographic.
Related Concept Videos
Toxoplasmosis
Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...
American Trypanosomiasis
Chagas disease, or American trypanosomiasis, is a vector-borne parasitic infection caused by Trypanosoma cruzi, a flagellated protozoan (kinetoplastid) of the family Trypanosomatidae. The disease is endemic in Latin America, although cases are increasingly reported worldwide due to human migration. Transmission most commonly occurs when feces of infected triatomine bugs contaminate bite wounds or mucosal surfaces; additional routes include congenital, transfusional, transplant-related, and oral...
Amebiasis
Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...

