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Related Experiment Videos

Methanol in human breath

J Taucher1, A Lagg, A Hansel

  • 1Institut für Ionenphysik, Universität Innsbruck, Austria.

Alcoholism, Clinical and Experimental Research
|October 1, 1995
PubMed
Summary
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Human breath analysis using proton transfer reaction-mass spectrometry revealed increased methanol levels after consuming fruits or alcoholic beverages. These findings highlight breath analysis as a method for detecting ingested substances.

Area of Science:

  • Analytical Chemistry
  • Biochemistry
  • Physiology

Background:

  • Human breath contains trace gases reflective of metabolic processes and external exposures.
  • Non-invasive methods for analyzing breath composition are valuable for health monitoring.

Purpose of the Study:

  • To quantify methanol and ethanol concentrations in human breath.
  • To investigate the impact of fruit consumption and alcoholic beverage intake on breath methanol levels.

Main Methods:

  • Proton transfer reaction-mass spectrometry (PTR-MS) was employed for trace gas analysis.
  • Breath samples were collected from individuals after controlled consumption of fruits and alcoholic beverages.

Main Results:

  • Methanol concentrations in breath increased from a physiological level of ~0.4 ppm to ~2 ppm after consuming 0.5 kg of fruits.

Related Experiment Videos

  • Similar methanol concentrations (~2 ppm) were observed after ingesting 100 ml of brandy containing 0.19% methanol.

    • Conclusions:

    • Fruit consumption and alcohol intake significantly elevate breath methanol levels.
    • PTR-MS is a sensitive technique for detecting exogenous substances like methanol and ethanol in human breath.