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Related Experiment Videos

ABIOMED BVS 5000: experience and potential advantages

G K Jett1

  • 1Department of Cardiothoracic Surgery, Baylor University Medical Center, Dallas, Texas 75218, USA.

The Annals of Thoracic Surgery
|January 1, 1996
PubMed
Summary

The ABIOMED BVS 5000, a pulsatile assist device, effectively supports postcardiotomy patients, showing improved outcomes compared to nonpulsatile devices. This circulatory support system demonstrates safety and efficacy in clinical use.

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Area of Science:

  • Cardiovascular Surgery
  • Biomedical Engineering
  • Medical Devices

Background:

  • The ABIOMED BVS 5000 is an FDA-approved, two-chambered, extracorporeal pulsatile assist device for temporary circulatory support.
  • Initial FDA approval was granted in 1992 specifically for postcardiotomy patients.

Purpose of the Study:

  • To evaluate the efficacy and safety of the ABIOMED BVS 5000 in supporting postcardiotomy patients.
  • To compare the performance of the pulsatile BVS 5000 with nonpulsatile assist devices.

Main Methods:

  • Data collected from a worldwide registry of 500 patients using the BVS 5000.
  • Analysis of patient demographics, including the majority being postcardiotomy (53%) and requiring biventricular assist (65%).
  • Comparative analysis at Baylor University Medical Center between the BVS 5000 and nonpulsatile devices.

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Main Results:

  • Postcardiotomy patients supported by the BVS 5000 achieved a 27% discharge rate.
  • Cardiomyopathy patients showed a higher discharge rate exceeding 40%.
  • The BVS 5000 demonstrated superior wean rates (60% vs. 47%) and discharge rates (27% vs. 17%) compared to nonpulsatile devices in comparative analysis.

Conclusions:

  • The ABIOMED BVS 5000 is capable of supporting postcardiotomy patients, as evidenced by registry data and single-center experience.
  • The device is considered safe, simple to use, and effective for circulatory support.
  • The pulsatile nature of the BVS 5000 appears to provide advantages over nonpulsatile circulatory support systems.