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Related Experiment Videos

Extended support with permanent systems: percutaneous versus totally implantable

D G Pennington1

  • 1Department of Surgery, St. Louis University Medical Center, Missouri, USA.

The Annals of Thoracic Surgery
|January 1, 1996
PubMed
Summary

The Novacor left ventricular assist system offers reliable long-term support for patients awaiting heart transplants. Despite risks like infection and thromboembolism, these devices show feasibility for permanent implantation as a transplant alternative.

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Area of Science:

  • Cardiovascular Surgery
  • Biomedical Engineering
  • Transplantation Medicine

Background:

  • Circulatory support devices are crucial for patients awaiting heart transplantation.
  • Long-term device performance data is essential for clinical decision-making.

Purpose of the Study:

  • To evaluate the long-term reliability and challenges of the Novacor left ventricular assist system.
  • To assess the feasibility of permanent, totally implantable left ventricular assist devices as a bridge to or alternative for transplantation.

Main Methods:

  • Analysis of long-term usage data for the Novacor left ventricular assist system.
  • Identification and assessment of complications associated with device use, including infection and thromboembolism.
  • Evaluation of issues related to compliance chambers.

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Main Results:

  • The Novacor system demonstrates reliability for extended patient support.
  • Infection and thromboembolism, while present, do not appear to preclude long-term device utilization.
  • Observed problems with compliance chambers are less significant than initially anticipated.

Conclusions:

  • The Novacor left ventricular assist system is a viable option for long-term circulatory support.
  • Permanent, totally implantable left ventricular assist devices are feasible for patients who are candidates for heart transplantation.