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Behavioral disturbance in dementia

C Lloyd1, R J Hafner, G Holme

  • 1Dibden Research Unit, Glenside Hospital, Eastwood, Australia.

Journal of Geriatric Psychiatry and Neurology
|October 1, 1995
PubMed
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Behavioral disturbance strongly correlates with cognitive impairment in dementia patients, particularly Alzheimer's disease. Medication showed limited effectiveness, emphasizing the need for behavioral programs.

Area of Science:

  • Geriatric Psychiatry
  • Neurology
  • Psychology

Background:

  • Moderate to severe dementia impacts cognitive function and behavior.
  • Alzheimer's disease is a leading cause of dementia.
  • Behavioral disturbances are common in dementia patients.

Purpose of the Study:

  • To investigate the correlation between cognitive impairment and behavioral disturbance in dementia patients.
  • To assess the reliability and equivalence of cognitive assessment tools.
  • To evaluate the effectiveness of medication in managing behavioral issues.

Main Methods:

  • Fifty-seven dementia patients (49 with Alzheimer's disease) were assessed twice over 8 weeks.
  • Cognitive function was measured using the Mini-Mental State Examination (MMSE) and Blessed Information-Memory-Concentration Test (BIMC).

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  • Behavioral disturbance was assessed using the Stockton Geriatric Rating Scale (SGRS).
  • Main Results:

    • A strong positive correlation was found between cognitive impairment and behavioral disturbance.
    • MMSE and BIMC scores showed high correlation (.87 at entry, .92 at exit), indicating broad equivalence.
    • All three measures demonstrated high test-retest reliability.
    • Medication was largely ineffective for severe behavioral disturbance.

    Conclusions:

    • Cognitive impairment severity is closely linked to behavioral disturbance in dementia.
    • MMSE and BIMC are reliable and equivalent measures for cognitive assessment in this population.
    • Effective behavioral programs are crucial for managing severe behavioral disturbance in dementia, as medication has limited utility.