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Primary prevention in patients with coronary heart disease: the APSIS study
N Rehnqvist1, P Hjemdahl, I Björkander
1Department of Medicine, Danderyd Hospital, Sweden.
Cardiovascular Drugs and Therapy
|August 1, 1995
Abstract:
Symptomatic treatment of patients with angina pectoris is well established and consists of nitrates, calcium antagonists, or beta-blockers. All these drugs improve symptomatology and reduce signs of ischemia on exercise test or long-term electrocardiogram recordings. It is not known, however, whether these drugs also improve prognosis. The only drug shown to improve prognosis is aspirin. In order to study the prognostic effect of calcium antagonists and beta-blockers, these two drugs were compared in the APSIS study.