Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Summer-type hypersensitivity pneumonitis

M Ando1, M Suga, Y Nishiura

  • 1First Department of Internal Medicine, Kumamoto University School of Medicine.

Internal Medicine (Tokyo, Japan)
|August 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hydroxyl radical production by H2O2 plus Cu,Zn-superoxide dismutase reflects the activity of free copper released from the oxidatively damaged enzyme.

The Journal of biological chemistry·1992
Same author

In situ morphology of the foramen ovale in the fetal and neonatal rat.

Pediatric research·1992
Same author

[Mechanisms of clearance of foreign bodies by macrophages].

Nihon Kyobu Shikkan Gakkai zasshi·1992
Same author

Mutations in c-K-ras 2 gene codon 12 during colorectal tumorigenesis in familial adenomatous polyposis.

Gastroenterology·1992
Same author

Type 3 GM1 gangliosidosis: characteristic MRI findings correlated with dystonia.

Acta neurologica Scandinavica·1992
Same author

Dislocation of the carpal scaphoid associated with median nerve compression: case report.

The Journal of trauma·1992
Same journal

A Possible Case of Drug-induced ANCA-associated Vasculitis Associated with Mirabegron.

Internal medicine (Tokyo, Japan)·2026
Same journal

Microangiopathic Hemolytic Anemia Due to Disseminated Carcinomatosis of the Bone Marrow in Esophageal Adenocarcinoma.

Internal medicine (Tokyo, Japan)·2026
Same journal

Recurrent Sigmoid Diverticulitis Managed with Adjunctive Daiobotanpito: A Case Report.

Internal medicine (Tokyo, Japan)·2026
Same journal

Tracheobronchial mucormycosis.

Internal medicine (Tokyo, Japan)·2026
Same journal

A Case of Transient ACTH and Cortisol Suppression Caused by Dexamethasone Mouthwash during Immune Checkpoint Inhibitor Treatment.

Internal medicine (Tokyo, Japan)·2026
Same journal

Acute Spinal Calcium Pyrophosphate Dehydrate Deposition Disease.

Internal medicine (Tokyo, Japan)·2026
See all related articles

Summer-type hypersensitivity pneumonitis (SHP) is an allergic lung disease caused by Trichosporon cutaneum mold. Diagnosis is aided by detecting anti-T. cutaneum antibodies, and eliminating the mold prevents recurrence.

Area of Science:

  • Pulmonary Medicine
  • Environmental Health
  • Mycology

Background:

  • Summer-type hypersensitivity pneumonitis (SHP) is a prevalent form of hypersensitivity pneumonitis (HP) in Japan.
  • It is linked to seasonal mold contamination within domestic environments.
  • The primary causative agent identified is the fungus Trichosporon cutaneum.

Purpose of the Study:

  • To elucidate the etiology and diagnostic markers of Summer-type hypersensitivity pneumonitis (SHP).
  • To understand the role of Trichosporon cutaneum in the pathogenesis of SHP.
  • To discuss the diagnostic utility of anti-T. cutaneum antibody assays and prevention strategies.

Main Methods:

  • Identification of Trichosporon cutaneum as the causative agent.
  • Investigation of the fungal components responsible for antigenicity, such as Glucuronoxylomannan.

Related Experiment Videos

  • Evaluation of anti-T. cutaneum antibody levels for diagnostic purposes.

    • Main Results:

    • Trichosporon cutaneum, found in warm, decaying organic matter, releases airborne spores that sensitize susceptible individuals.
    • Glucuronoxylomannan, a component of T. cutaneum, exhibits potent antigenicity, leading to granulomatous alveolitis.
    • Anti-T. cutaneum antibody assays demonstrate high positivity in SHP patients, proving useful for diagnosis.

    Conclusions:

    • Eliminating T. cutaneum from the environment is crucial for preventing disease recurrence.
    • SHP, initially thought to be unique to Japan, has been identified in Korea, suggesting a broader geographical distribution.
    • The condition is expected to be increasingly recognized in temperate and tropical climates worldwide.