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Updated: Aug 14, 2026
07:37
Roux-en-Y Gastric Bypass Operation in Rats
Published on: June 11, 2012
Physical and psychological complications after intestinal bypass for obesity
Canadian Medical Association Journal
|April 23, 1977
Summary
Jejunoileal shunt surgery for obesity can cause vitamin and magnesium deficiencies, leading to cognitive and mood changes. Supplementation improved symptoms, demonstrating a link between nutrient levels and patient well-being.
Area of Science:
- Nutritional Science
- Gastroenterology
- Psychiatry
Background:
- Jejunoileal bypass surgery is a bariatric procedure for massive obesity.
- Malabsorption is a known complication of jejunoileal bypass surgery.
Observation:
- A 33-year-old woman developed cognitive changes, depression, arthralgia, and dermatitis 5 years post-surgery.
- Dermatitis and low serum vitamin C and carotene suggested deficiencies.
- Low serum magnesium levels were also detected.
Findings:
- Vitamin and mineral replacement therapy improved both physical and psychological symptoms.
- Cognitive and psychological improvements were objectively measured using standardized tests.
- Symptom amelioration was sustained at an 18-month follow-up.
Implications:
- Jejunoileal shunt surgery can lead to significant vitamin and magnesium deficiencies.
- These deficiencies can manifest as diverse physical and psychological symptoms.
- Nutritional and mineral repletion is crucial for managing post-surgical complications and improving patient outcomes.
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