Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

MR imaging of malignant soft-tissue tumors

S L Hanna1, B D Fletcher

  • 1Department of Radiology, University of Tennessee, Memphis, USA.

Magnetic Resonance Imaging Clinics of North America
|November 1, 1995
PubMed
Summary

Magnetic resonance imaging (MRI) is crucial for diagnosing soft-tissue sarcomas. Contrast-enhanced MRI aids in distinguishing recurrent tumors from postoperative fluid collections, improving patient management.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Radiologic approach to the diagnosis of pulmonary disorders in premature infants.

Pediatric annals·2014
Same author

Epithelioid sarcoma: clinical, MR imaging and pathologic findings.

Skeletal radiology·2002
Same author

Magnetic resonance imaging detection of avascular necrosis of the bone in children receiving intensive prednisone therapy for acute lymphoblastic leukemia or non-Hodgkin lymphoma.

Leukemia·2001
Same author

Dynamic magnetic resonance imaging of regional contrast access as an additional prognostic factor in pediatric osteosarcoma.

Cancer·2001
Same author

Thallium bone imaging as an indicator of response and outcome in nonmetastatic primary extremity osteosarcoma.

Pediatric radiology·2001
Same author

Predominance of HIV type 1 subtype G among commercial sex workers from Kinshasa, Democratic Republic of Congo.

AIDS research and human retroviruses·2001

Area of Science:

  • Oncology
  • Radiology
  • Medical Imaging

Background:

  • Soft-tissue sarcomas are diagnosed in nearly 6000 individuals annually.
  • Magnetic resonance imaging (MRI) is the primary tool for detecting, staging, and monitoring soft-tissue sarcomas due to its superior tissue contrast.

Purpose of the Study:

  • To outline the utility of MRI in soft-tissue sarcoma evaluation.
  • To describe characteristic MRI findings of soft-tissue sarcomas.
  • To highlight the role of contrast agents in differentiating tumor recurrence from postoperative changes.

Main Methods:

  • Review of MRI characteristics of soft-tissue sarcomas.
  • Discussion of imaging features indicative of malignancy.
  • Evaluation of the impact of paramagnetic contrast agents.

Main Results:

  • Soft-tissue sarcomas typically show muscle-like intensity on T1-weighted images and intermediate to high signal intensity relative to fat on T2-weighted images.
  • While irregular margins, bone invasion, and vascular encasement suggest malignancy, some sarcomas are well-circumscribed.
  • Paramagnetic contrast agents enhance the differentiation between recurrent tumors and postoperative fluid collections.

Conclusions:

  • MRI is indispensable for the comprehensive management of soft-tissue sarcomas.
  • Understanding typical MRI signal characteristics and the judicious use of contrast agents are key for accurate diagnosis and treatment monitoring.

Related Experiment Videos