Botulinum toxin therapy for blepharospasm in the otolaryngology clinic

The use of botulinum toxin (Botox, Allergan, Inc.) is a treatment for spasmodic conditions involving many structures in the head and neck. Proper reconstitution, storage, preparation and administration of Botox are important aspects of its use. This article focuses on the actual preparation and sites of injection of Botox as well as the authors' clinical experiences in using it.