[A clinical and experimental study of L-form bacteria in 66 cases]

In order to study the relationship between the time for establishing the diagnosis of infectious diseases and L-form bacteria, a series of clinical specimens taken from 321 cases of patients suspected to have infection were collected. Besides routine bacterial culture, special culture for L-form bacteria was also performed. The results were as follows: the rate of positive routine bacterial culture was 10.90% (35/321); the rate of negative routine bacterial culture but positive L-form bacterial culture was 20.56% (66/321). In this study, L-form bacteria infection was treated with sensitive antibiotics and a satisfactory result was obtained. It is shown that L-form bacterial culture is very useful in detection of pathogenic bacteria and helpful to the therapy of infectious diseases. Ultrastructure organization of these bacteria was studied by using transmission electron microscope.