[Implantable catheter systems. Experiences with 1000 patients with central venous ports]
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H J Kock1, U Krause, M Pietsch
1Abteilung für Allgemeine Chirurgie, Chirurgische Klinik und Poliklinik, Universität Essen.
Objective:
To assess retrospectively duration of functioning and rate of complications of a totally implantable venous access system used for long-term chemotherapy.
Patients And Methods:
Between 1985 and 1993, a central venous access system (Port-a-Cath) had been implanted subcutaneously for long-term chemotherapy in 1000 patients (479 males, 521 females; mean age 49 [15-86] years). Follow-up observations lasted until the end of the chemotherapy or the removal of the system.
Results:
Mean time of functioning of the catheter system was 284 (2-1563) days. The complication rate was 12.8%: catheter infection in 4.9% and catheter thrombosis in 3.2%. A further 4.7% of patients had less common complications (malfunction, catheter dislocation, skin necrosis, catheter break or disconnection, pneumothorax). A total of 119 (11.9%) systems had to be removed because of complications. The rates of infection and of other complications were significantly lower in patients with solid tumours (2 and 4%, respectively) than in those with haematological disease (6 and 8%) (P < 0.05 for each).
Conclusion:
Totally implantable venous access systems are suitable for long-term chemotherapy and cause few complications.