Related Experiment Video
Updated: Aug 13, 2026
Establishment of an Embryo Implantation Model In Vitro
Published on: June 21, 2024
A model for the incorporation of intracytoplasmic sperm injection into a private practice in vitro fertilization
W B Schoolcraft1, T Schlenker, A Adler
1Center for Reproductive Medicine, Englewood, Colorado, USA.
Objective:
To describe a method for the training of personnel and the implementation of intracytoplasmic sperm injection (ICSI) into an IVF program. The results of the first 75 cycles are reviewed.
Design:
Retrospective review of the first 75 consecutive ICSI procedures.
Setting:
Private, community-based IVF program.
Main Outcome Measures:
The fertilization rate, damage rate, ongoing pregnancy rate (PR), and implantation rate were measured.
Results:
Nine percent of the injected oocytes were damaged. The fertilization rate was 60%, and the cleavage rate was 98%. Fifty-nine percent of the cycles resulted in an ongoing pregnancy, and the implantation rate per embryo was 26%.
Conclusions:
A high initial PR can be obtained with ICSI using a systematic training regimen.
