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Determination of manganese in human brain samples
Forensic Science International
|December 29, 1995
Summary
A new method accurately measures manganese (Mn) in human brain tissue using graphite furnace atomic absorption spectrophotometry (GFAAS). This technique aids in assessing Mn accumulation from occupational or medical exposures.
Area of Science:
- Toxicology
- Analytical Chemistry
- Neuroscience
Background:
- Manganese (Mn) is an essential element, but excessive accumulation in the brain can lead to neurotoxicity.
- Occupational and iatrogenic exposures are potential sources of elevated Mn levels.
- Accurate post-mortem assessment of Mn in human brain tissue is crucial for understanding exposure-related neurological conditions.