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Serious renal disease in Egypt

M A Essamie1, A Soliman, T M Fayad

  • 1Division of Nephrology, University of Cairo, Egypt.

The International Journal of Artificial Organs
|May 1, 1995
PubMed
Summary

This study on renal disease in Egypt found diabetes and Schistosoma as top causes of kidney failure. Acute renal failure, especially iatrogenic-toxic, is a growing concern in Egyptian nephrology patients.

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Area of Science:

  • Nephrology
  • Epidemiology
  • Public Health

Background:

  • Serious renal disease poses a significant health challenge in Egypt.
  • Understanding the prevalence and causes of kidney failure is crucial for public health initiatives.

Purpose of the Study:

  • To investigate the spectrum of serious renal disease in Egyptian patients.
  • To identify the primary etiologies of chronic and acute renal failure.
  • To assess outcomes including mortality and treatment modalities.

Main Methods:

  • Prospective registration of 155 patients at the University of Cairo nephrology service over 62 days in 1993.
  • Analysis of patient demographics, clinical presentation, laboratory values (creatinine, urea), and renal biopsy findings.
  • Categorization of renal failure into acute and chronic, with sub-classification of acute renal failure.

Main Results:

  • High admission creatinine (804 mumol/l) and urea (64 mmol/l) levels observed.
  • 15% mortality rate; 115 patients underwent dialysis.
  • Diabetes mellitus type II and Schistosoma were the most common causes of end-stage renal failure.
  • Mesangio-capillary glomerulonephritis was the most frequent diagnosis on renal biopsy.
  • Increasing prevalence of acute renal failure, particularly iatrogenic-toxic, noted.

Conclusions:

  • Diabetes and Schistosoma are key drivers of chronic kidney failure in Egypt.
  • Acute renal failure, including iatrogenic causes, is a rising concern.
  • Effective management strategies and preventative measures are needed to address the burden of renal disease.

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