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A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
Published on: May 14, 2013
Intra-coronary stents--extending the role of angioplasty in angina--initial experience
R G Sheahan1, G F Gearty, M J Walsh
1Trinity Cardiology, St James's Hospital, Dublin.
Insights
Intracoronary stents improve outcomes for percutaneous transluminal coronary angioplasty (PTCA) by managing restenosis and dissection. Stenting reduces the need for coronary artery bypass grafting after angioplasty.
Area of Science:
- Interventional Cardiology
- Vascular Surgery
- Biomedical Engineering
Background:
- Percutaneous transluminal coronary angioplasty (PTCA) is a common revascularization technique.
- Despite advancements, restenosis rates after PTCA remain a significant challenge.
- Therapeutic agents have shown limited success in improving PTCA outcomes.
Abstract:
Percutaneous transluminal coronary angioplasty (PTCA) is a widely successful revascularisation procedure. The restenosis rate has not significantly improved, despite the addition of many therapeutic agents. We describe the role of intra-coronary stents in the management of recurrent occlusion, restenosis and intracoronary dissection. We describe and discuss the problems associated with placement of the stent. The intracoronary stent has a successful adjuvant role to play with angioplasty in reducing both the elective and emergency requirements for coronary artery bypass grafting.
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