Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Visualizing life on biomembranes by atomic force microscopy

H Oberleithner1, E Brinckmann, G Giebisch

  • 1University of Würzburg, Department of Physiology, Germany.

Kidney International
|October 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

CO<sub>2</sub> gas exchange and transpiration of Welwitschia mirabilis Hook. fil. in the central Namib desert.

Oecologia·2017
Same author

Leaf temperatures and energy balance ofWelwitschia mirabilis in its natural habitat.

Oecologia·2017
Same author

The effect of different growing conditions on water relations parameters of leaf epidermal cells of Tradescantia virginiana L.

Oecologia·2017
Same author

Water loss and malate fluctuations during the day for plants in the southern Namib desert.

Oecologia·2017
Same author

CO2 exchange of CAM exhibiting suceulents in the southern Namib desert in relation to microclimate and water stress.

Photosynthesis research·2014
Same author

CO2 exchange of CAM exhibiting succulents in the southern Namib desert in relation to microclimate and water stress.

Photosynthesis research·2014
Same journal

KDIGO Life Cycle of Guideline Development Series Part 6: Bridging the Gap between Guidelines and Clinical Practice: The KDIGO Approach to Global Implementation and Education in Nephrology.

Kidney international·2026
Same journal

KDIGO Life Cycle of Guideline Development Series Part 5: Guideline updates and a living model for the future.

Kidney international·2026
Same journal

Crystal-storing histiocytosis causing severe acute kidney injury.

Kidney international·2026
Same journal

Peritoneal dialysis in a patient with extensive burn scarring.

Kidney international·2026
Same journal

COPA syndrome unmasked by anti-neutrophil cytoplasmic antibody-positive immune-complex nephritis.

Kidney international·2026
Same journal

Monitoring anti-nephrin antibodies in the management of recurrent diffuse podocytopathy.

Kidney international·2026
See all related articles

Atomic force microscopy (AFM) images hard surfaces with atomic resolution. This review introduces AFM for biologists, highlighting its use in visualizing soft biological samples like cell membranes and nuclear pores.

Area of Science:

  • Biophysics
  • Cell Biology
  • Microscopy

Background:

  • Atomic Force Microscopy (AFM) is a powerful near-field microscope invented in 1986.
  • AFM routinely achieves atomic resolution for hard sample surfaces.
  • Imaging soft biological samples with AFM remains a significant challenge.

Purpose of the Study:

  • Introduce AFM technique to experimental biologists.
  • Review recent data on imaging molecular structures of biomembranes.
  • Provide detailed applications of AFM in biological contexts.

Main Methods:

  • AFM principles and capabilities for biological imaging.
  • Analysis of plasma membrane dynamics in migrating renal epithelial cells.
  • Visualization of nuclear pore complexes in kidney cells.

Related Experiment Videos

Main Results:

  • Demonstrated AFM's utility in imaging dynamic cellular processes.
  • Successfully visualized macromolecular structures within the nuclear envelope.
  • Highlighted AFM's potential for high-resolution analysis of biomembranes.

Conclusions:

  • AFM is a valuable tool for experimental biologists studying soft biological samples.
  • AFM enables detailed investigation of biomembrane molecular structures and cellular dynamics.
  • Future applications of AFM in cell biology are promising.