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Aetiopathogenesis of Takayasu's arteritis and BCG vaccination: the missing link?
1Department of Cardiology, All India Institute of Medical Sciences, New Delhi, India.
Abstract:
Takayasu's arteritis is an inflammatory disease of unknown aetiology involving the aorta, its major branches and pulmonary arteries. Historical, epidemiological and immunological data are presented which suggest that BCG vaccination in the susceptible host might be important in the pathogenesis of Takayasu's arteritis. This hypothesis best explains the various known facts about the disease.
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