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Arthritis without grains caused by Pseudallescheria boydii
G Ginter1, G S de Hoog, A Pschaid
1Department of Dermatology, University of Graz, Austria.
Mycoses
|September 1, 1995
Summary
A severe knee joint infection caused by Pseudallescheria boydii in a young woman led to cartilage destruction. Successful treatment with miconazole-itraconazole was achieved over four months with no adverse effects.
Area of Science:
- Mycology
- Infectious Diseases
- Orthopedics
Background:
- Pseudallescheria boydii is a rare fungal pathogen that can cause severe infections.
- Knee joint infections can lead to significant joint damage and disability.
Observation:
- A 23-year-old female presented with a severe knee joint infection due to Pseudallescheria boydii.
- The infection resulted in complete destruction of the articular cartilage.
- The possibility of fungal entry through minor skin abrasions was considered.
Findings:
- The clinical presentation was compared to infections caused by Scedosporium prolificans.
- A four-month course of combined antimycotic therapy with miconazole and itraconazole was administered.
- The treatment was successful in resolving the infection.
Implications:
- This case highlights the potential for Pseudallescheria boydii to cause severe joint infections.
- Early diagnosis and appropriate antifungal treatment are crucial for favorable outcomes.
- The findings suggest that miconazole and itraconazole are effective in treating Pseudallescheria boydii knee joint infections.