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[Acute pancreatitis caused by metronidazole]

F E de Jongh1, J P Ottervanger, P C Stuiver

  • 1Havenziekenhuis, afd. Inwendige Geneeskunde en Tropische Ziekten, Rotterdam.

Nederlands Tijdschrift Voor Geneeskunde
|January 6, 1996
PubMed
Summary

Metronidazole can cause acute pancreatitis, a rare but serious side effect. Symptoms resolved after discontinuing the medication, highlighting a potential link between metronidazole use and pancreatitis.

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Area of Science:

  • Gastroenterology
  • Pharmacology

Background:

  • Metronidazole is a widely used antibiotic.
  • Adverse drug reactions require careful monitoring.

Observation:

  • A patient experienced recurrent acute pancreatitis between 1988 and 1995.
  • Each pancreatitis episode coincided with metronidazole use.

Findings:

  • Pancreatitis symptoms resolved upon metronidazole withdrawal.
  • This suggests metronidazole as a potential cause of pancreatitis in this case.

Implications:

  • Metronidazole-induced pancreatitis is a rare but significant adverse event.
  • Further research is needed to understand the mechanism of metronidazole-induced pancreatitis.

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