Temporal patterns of heart rate and blood pressure in elders

S B Dunbar1, L Farr

  • 1Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA, USA.

Nursing Research
|January 1, 1996
PubMed

Insights

Elderly individuals with heart disease showed more predictable circadian rhythms in heart rate and blood pressure compared to healthy elders. Standardized cardiac medication timing may influence these cardiovascular rhythms.

Area of Science:

  • Gerontology
  • Cardiovascular Physiology
  • Chronobiology

Background:

  • Circadian rhythms significantly influence physiological processes, including cardiovascular function.
  • Age-related changes and heart disease can alter these biological rhythms.
  • Understanding these patterns is crucial for optimizing health assessments in older adults.

Purpose of the Study:

  • To compare circadian patterns of cardiovascular parameters between elderly individuals with and without heart disease.
  • To investigate the influence of health status and medication on cardiovascular rhythmicity in older adults.
  • To identify potential implications for timing cardiac assessments in the elderly.

Main Methods:

  • Cosinor analysis was used to assess circadian rhythm parameters.
  • Automated measurements of heart rate, systolic blood pressure, and diastolic blood pressure were taken every 2 hours for 4 days.
  • Activity-rest patterns, demographics, and medication profiles were recorded and analyzed.

Main Results:

  • Elderly individuals with heart disease exhibited more pronounced rhythms in rate-pressure product compared to the control group.
  • The cardiac group demonstrated more synchronized oscillations in heart rate and systolic blood pressure rhythms.
  • These differences were potentially linked to standardized cardiac medication administration schedules.

Conclusions:

  • Standardized medication timing may synchronize cardiovascular rhythms in elderly patients with heart disease.
  • Circadian patterns of heart rate and blood pressure in elders may inform optimal timing for cardiac assessments.
  • Further research into chronotherapy could enhance cardiovascular care for the elderly.

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