Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Quantitative electroencephalographic analyses in cocaine-preferring polysubstance abusers during abstinence

R A Roemer1, A Cornwell, D Dewart

  • 1Department of Psychiatry, Temple University Health Sciences Center, Philadelphia, PA 19140, USA.

Psychiatry Research
|October 16, 1995
PubMed
Summary

Quantitative electroencephalography (QEEG) in cocaine polysubstance abuse recovery reveals altered brainwave patterns, including reduced delta and theta power and increased relative alpha and beta power, indicating potential neurological changes.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Search for Low-Mass Dijet Resonances Using Trigger-Level Jets with the ATLAS Detector in pp Collisions at sqrt[s]=13  TeV.

Physical review letters·2018
Same author

Search for the Decay of the Higgs Boson to Charm Quarks with the ATLAS Experiment.

Physical review letters·2018
Same author

Search for a Structure in the B_{s}^{0}π^{±} Invariant Mass Spectrum with the ATLAS Experiment.

Physical review letters·2018
Same author

Search for High-Mass Resonances Decaying to τν in pp Collisions at sqrt[s]=13  TeV with the ATLAS Detector.

Physical review letters·2018
Same author

Search for Heavy Higgs Bosons A/H Decaying to a Top Quark Pair in pp Collisions at sqrt[s]=8  TeV with the ATLAS Detector.

Physical review letters·2017
Same author

Search for Dark Matter Produced in Association with a Higgs Boson Decaying to bb[over ¯] Using 36  fb^{-1} of pp Collisions at sqrt[s]=13  TeV with the ATLAS Detector.

Physical review letters·2017

Area of Science:

  • Neuroscience
  • Psychiatry
  • Quantitative Electroencephalography (QEEG)

Background:

  • Polysubstance abuse, particularly involving cocaine, can lead to significant neurophysiological alterations.
  • Understanding the long-term brain activity changes in individuals recovering from substance use disorders is crucial for effective treatment and relapse prevention.
  • Quantitative electroencephalography (QEEG) offers a non-invasive method to assess brain electrical activity patterns.

Purpose of the Study:

  • To investigate the quantitative electroencephalographic (QEEG) patterns in individuals recovering from polysubstance abuse with a history of cocaine use.
  • To identify specific alterations in brainwave frequencies (delta, theta, alpha, beta) and their power distributions.
  • To examine interhemispheric coherence and frontal asymmetry in the QEEG profiles of this population.

Related Experiment Videos

Main Methods:

  • QEEG data were collected from 90 subjects recovering from polysubstance abuse (median 90 days abstinent), with a history of preferential cocaine use.
  • Analysis focused on absolute and relative power in delta, theta, alpha, and beta frequency bands.
  • Interhemispheric coherence and frontal asymmetry were assessed, alongside the identification of atypical EEG patterns.

Main Results:

  • Significant decreases in absolute and relative delta power and absolute and relative theta power were observed compared to normative data.
  • Increased relative, but not absolute, alpha and beta power were found.
  • Frontal delta, theta, and alpha power showed asymmetry (right > left), and reduced interhemispheric coherence was noted in delta, theta, and frontal beta bands. Atypical paroxysmal-like alpha patterns were present in approximately half the subjects.

Conclusions:

  • Individuals recovering from cocaine-preferential polysubstance abuse exhibit distinct QEEG abnormalities, including reduced slow-wave activity and altered fast-wave activity.
  • Observed frontal asymmetry and reduced interhemispheric coherence suggest disruptions in functional brain connectivity.
  • The presence of atypical EEG patterns highlights the complex neurophysiological sequelae of polysubstance abuse, potentially impacting cognitive function and recovery.