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A Murine Model of Irreversible and Reversible Unilateral Ureteric Obstruction
Published on: December 20, 2014
[A detubularized reservoir for the urine made from the small intestine]
Abstract:
In the department of urology of the Georgian Cancer Research Center creation of small intestinal detubularized reservoir for urine was practiced for 4 years (1990-1994). Of a total of 35 patients, 27 underwent cystectomy for bladder cancer, whereas 8 patients with secondary cancer of the bladder and rectum were subjected to exenteration of the small pelvis organs. In 29 patients the reservoir was made using invagination valvular mechanism (in 6 cases according to D. Skinner, in 23 according to an original technique). Non-invagination valvular device according to the authors' technique was used in the other 6 patients (group 3). In postoperative period 3 patients died. A mean follow-up lasted 18 months. With time, the reservoir volume increased with a parallel fall in pressure. Anatomical conditions of the kidneys compared to the baseline conditions have improved, reflux pyelonephritis was absent. Adequate valvular function recovered in group 3. Rejection of invagination valves diminishes the duration of the surgery, makes the operative procedure easier. Introduction of the original non-invagination valvular device proves to reliable sealing and easy catheterization of the reservoir.
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