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Diphenylhydantoin-induced acute renal failure
Nephron
|January 1, 1977
Summary
Diphenylhydantoin can cause acute renal failure as a hypersensitivity reaction. Prompt withdrawal of the drug and corticosteroid treatment can restore normal kidney function.
Area of Science:
- Nephrology
- Clinical Pharmacology
- Immunology
Background:
- Diphenylhydantoin (phenytoin) is an anticonvulsant medication.
- Drug-induced hypersensitivity reactions can affect multiple organ systems, including the kidneys.
- Acute renal failure is a serious adverse effect that requires prompt diagnosis and management.