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Central nervous system granulocytic sarcoma in a patient with essential thrombocythemia
1Second Institute of Medical Clinics, University of Bari, Italy.
American Journal of Hematology
|January 1, 1996
Abstract:
We report a rare case of central nervous system granulocytic sarcoma (GS) in a patient with essential thrombocythemia (ET). The diagnosis of GS was established by morphological and cytochemical findings (peroxidase and naphthol-AS-D-chloroacetate esterase positivity) of neoplastic cells. GS was detected as an intracranial frontal mass 7 months before the transformation of ET in acute myeloid leukemia and relapsed as two extradural spinal masses during the course of leukemic evolution.