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Related Experiment Videos

[Statistical contribution on symptomatic dry eye]

K W Ruprecht, W Giere, K G Wulle

    Ophthalmologica. Journal International D'Ophtalmologie. International Journal of Ophthalmology. Zeitschrift Fur Augenheilkunde
    |January 1, 1977
    PubMed
    Summary
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    A significant number of patients experience a gritty sensation in their eyes. This study found that 4.5% of patients have keratoconjunctivitis sicca, with hormonal imbalances noted in affected women.

    Area of Science:

    • Ophthalmology
    • Endocrinology

    Context:

    • A study evaluated patient-reported symptoms using optical mark page reader forms.
    • The symptom 'feeling of sand in the eye' was investigated in 5,833 patients.

    Purpose:

    • To determine the prevalence of keratoconjunctivitis sicca (dry eye disease) based on a specific symptom.
    • To investigate potential underlying causes, including hormonal imbalances, in patients diagnosed with dry eye disease.

    Summary:

    • 11.7% of patients reported a gritty sensation; 4.5% were diagnosed with keratoconjunctivitis sicca after ophthalmological examination.
    • The Bengal-Rosa 1% test and slit-lamp microscopy confirmed dry eye signs.
    • In women with confirmed dry eye, 25 out of 53 showed sex hormone imbalances, alongside other potential causes like autoimmune diseases.

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    Impact:

    • Highlights the prevalence of dry eye disease and the significance of patient-reported symptoms.
    • Suggests a link between sex hormone imbalances and dry eye disease in women.
    • Underscores the importance of thorough ophthalmological examination for diagnosing and managing dry eye conditions.