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Coronary artery bypass grafting in a patient with antiphospholipid syndrome
N Sakakibara1, M Kawasuji, Y Matsumoto
1Department of Surgery (I), Kanazawa University School of Medicine, Japan.
Insights
Antiphospholipid syndrome can cause severe coronary artery disease and thrombosis in young adults. Early consideration of this condition is crucial for diagnosing myocardial infarction in this demographic.
Area of Science:
- Cardiology
- Rheumatology
- Vascular Medicine
Background:
- Antiphospholipid syndrome (APS) is an autoimmune disorder associated with an increased risk of thrombosis.
- Severe coronary artery disease (CAD) is uncommon in young patients without traditional risk factors.
Observation:
- A 32-year-old female patient presented with severe CAD and multiple arterial and venous thromboses.
- The patient exhibited occlusion of the right internal thoracic artery, stenosis of the left internal thoracic artery, and left saphenous vein occlusion.
Findings:
- Coronary artery bypass grafting (CABG) was successfully performed using the right gastroepiploic artery and a right saphenous vein graft.
- The patient's thrombotic events were attributed to antiphospholipid syndrome.
Implications:
- This case highlights the importance of considering antiphospholipid syndrome in young patients presenting with myocardial infarction.
- Early diagnosis and management of APS can prevent severe cardiovascular complications.
Abstract:
We report a 32-year-old female patient with antiphospholipid syndrome including severe coronary artery disease and multiple arterial and venous thrombosis. The patient had occlusion of the right internal thoracic artery, diffuse stenosis of the left internal thoracic artery, and occlusion of the left saphenous vein. The patient underwent successful coronary artery bypass grafting using the right gastroepiploic artery and a segment of the right saphenous vein. Antiphospholipid syndrome should be considered in young patients with myocardial infarction.