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Related Experiment Videos

An improved left ventricular cannula for chronic dynamic blood pump support

J F Antaki1, T J Dennis, H Konishi

  • 1University of Pittsburgh, Artificial Heart and Lung Program, Pennsylvania 15219, USA.

Artificial Organs
|July 1, 1995
PubMed
Summary

A novel trumpet-shaped cannula tip prevents blockage in dynamic blood pumps. This design ensures optimal blood flow by maintaining proper placement within the ventricle, improving hemodynamic performance.

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Area of Science:

  • Biomedical Engineering
  • Cardiovascular Physiology
  • Medical Device Design

Background:

  • Dynamic blood pumps for ventricular unloading are crucial in treating heart failure.
  • Existing cannula tips can cause inflow occlusion due to negative pressure and intraventricular structures.
  • Cannula tip geometry significantly impacts the performance of ventricular unloading devices.

Purpose of the Study:

  • To develop and evaluate a novel "trumpet" mouth cannula tip for dynamic blood pumps.
  • To overcome the limitation of inflow occlusion caused by conventional cannula designs.
  • To assess the anatomic and hemodynamic interaction of the trumpet cannula within the ventricular apex.

Main Methods:

  • A novel "trumpet" mouth cannula was designed with specific criteria for apex stenting and tip placement.

Related Experiment Videos

  • In vivo evaluation of the prototype trumpet cannula against conventional designs (caged, blunt, tapered).
  • Assessment of anatomic and hemodynamic interaction within the ventricular apex, including post-mortem examination.

    • Main Results:

    • Post-mortem examination confirmed no myocardial obstruction in the inflow tract for all tested cannula designs.
    • The trumpet mouth cannula demonstrated satisfactory hemodynamic performance.
    • The novel design effectively addressed the issue of inflow occlusion.

    Conclusions:

    • The trumpet mouth cannula design is a promising solution to prevent inflow occlusion in dynamic blood pumps.
    • This design ensures proper tip placement and apex stenting, crucial for effective ventricular unloading.
    • Further studies are warranted to fully establish the clinical utility of the trumpet cannula.