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Related Experiment Videos

Pulsatile total artificial heart using a reversible rotary pump

S Fukunaga1, N Mitsui, H Hotei

  • 1First Department of Surgery, Hiroshima University School of Medicine, Japan.

Artificial Organs
|July 1, 1995
PubMed
Summary
This summary is machine-generated.

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Researchers developed an implantable artificial heart using a gear pump and four artificial valves. This novel device achieved pulsatile flow rates of 0.8-0.75 L/min, showing promise for cardiac replacement.

Area of Science:

  • Biomedical Engineering
  • Cardiovascular Devices
  • Medical Device Design

Background:

  • Heart failure necessitates advanced therapeutic solutions.
  • Artificial heart development aims to restore circulatory function.
  • Current artificial hearts face challenges in efficiency and biocompatibility.

Purpose of the Study:

  • To evaluate a novel pump circuit for potential use as an implantable artificial heart.
  • To assess the performance of a gear pump integrated with artificial heart valves.
  • To determine the pulsatile flow rates achievable by the artificial heart circuit.

Main Methods:

  • A pump circuit was constructed using a gear pump and four artificial heart valves (mitral, pulmonary arterial, aortic, tricuspid).
  • Valves were strategically placed at the inflow and outflow ports of the pump.

Related Experiment Videos

  • The system was designed to discharge pulsatile flow into systemic and pulmonary arteries by alternating rotation direction.

    • Main Results:

    • The artificial heart circuit successfully discharged pulsatile flows.
    • Measured flow rates ranged from 0.8 to 0.75 L/min at heart rates of 60-110 bpm.
    • These rates are approximately half the rated discharge of the gear pump (1.7 L/min).

    Conclusions:

    • The developed pump circuit demonstrates feasibility as a component of an implantable artificial heart.
    • The system's ability to generate pulsatile flow is a key step towards functional cardiac replacement.
    • Further optimization is needed to enhance flow rates and overall efficiency for clinical application.