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Initial clinical experience with the Baylor-Nikkiso centrifugal pump
S Ohtsubo1, K Naito, M Matsuura
1Department of Surgery, Baylor College of Medicine, Houston, TX 77030, USA.
Artificial Organs
|July 1, 1995
Summary
The new Baylor-Nikkiso centrifugal pump is a compact, clinically approved device that reduces blood trauma. Initial trials show it is reliable and suitable for cardiopulmonary bypass surgery.
Area of Science:
- Biomedical Engineering
- Cardiovascular Surgery
Background:
- Centrifugal pumps are crucial in cardiopulmonary bypass.
- Existing pumps can cause significant blood trauma and have limitations.
Purpose of the Study:
- To evaluate the clinical suitability of the newly developed Baylor-Nikkiso centrifugal pump.
- To assess the pump's hemocompatibility, durability, and hemodynamic performance.
Main Methods:
- In vitro and in vivo validation studies.
- 48-hour biventricular bypass durability tests in calves.
- Initial clinical trials in patients undergoing cardiopulmonary bypass surgery.
Main Results:
- The Baylor-Nikkiso pump is the most compact centrifugal pump (25 ml priming volume).
- It provides high flow (4 L/min at 300 mm Hg) while reducing blood trauma.
- Clinical trials demonstrated stable hemodynamics with no leakage or thrombus formation.
Conclusions:
- The Baylor-Nikkiso pump shows excellent hemocompatibility and reliability.
- Its compact design and performance make it suitable for cardiopulmonary bypass.
- Further clinical experience will confirm its long-term efficacy.