Related Experiment Videos
Mitochondrial nitric oxide synthase: a ubiquitous regulator of oxidative phosphorylation?
T E Bates1, A Loesch, G Burnstock
1Department of Neurochemistry, University of London, England.
Biochemical and Biophysical Research Communications
|January 5, 1996
Abstract:
In this article we demonstrate the immunocytochemical localization of nitric oxide synthase in mitochondria isolated from heart, skeletal muscle, and kidney, using a monoclonal antibody directed against the endothelial form of nitric oxide synthase. The possibility that mitochondrially located nitric oxide synthase is a ubiquitous regulator of mitochondrial oxidative phosphorylation in mammalian cells is discussed.