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Auditory brainstem response in obstructive sleep apnea patients

C Muchnik1, Y Rubel, Y Zohar

  • 1Department of Communication Disorders, Speech, Language and Hearing, Chaim Sheba Medical Center, Tel Hashomer, Israel.

Journal of Basic and Clinical Physiology and Pharmacology
|January 1, 1995
PubMed
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Auditory brainstem responses (ABR) show prolonged latencies in obstructive sleep apnea (OSA) patients. However, clinically significant ABR changes were found in only 10% of OSA patients.

Area of Science:

  • Neuroscience
  • Otolaryngology

Background:

  • Obstructive sleep apnea (OSA) is a common condition affecting sleep quality and potentially neurological function.
  • Auditory brainstem responses (ABR) are electrophysiological measures assessing the auditory pathway integrity.

Purpose of the Study:

  • To investigate auditory pathway function in patients with obstructive sleep apnea (OSA) using ABR.
  • To correlate ABR changes with OSA severity and evaluate the impact of uvulopalato-pharyngoplasty (UPPP).

Main Methods:

  • Recording ABR in 79 OSA patients (mild, moderate, severe) and 29 healthy controls.
  • Analyzing latency values of waves I, III, and V, and inter-wave transmission times.
  • Comparing preoperative and postoperative ABR in 36 patients who underwent UPPP.

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Main Results:

  • Statistically significant ABR wave I, III, and V latency prolongation in all OSA subgroups versus controls.
  • Prolonged inter-wave I-III and I-V transmission times in moderate and severe OSA.
  • Clinically significant ABR prolongation observed in only 10% of OSA patients.

Conclusions:

  • While OSA is associated with subclinical ABR latency changes, significant clinical impact is infrequent.
  • Uvulopalato-pharyngoplasty (UPPP) did not show significant postoperative changes in ABR.
  • ABR may serve as a sensitive tool for detecting subtle auditory pathway alterations in OSA.