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Left ventricular assist device options in pediatric patients
R C Ashton1, M C Oz, R E Michler
1Department of Surgery, Allegheny General Hospital, Pittsburgh, Pennsylvania, USA.
Summary
Pediatric left ventricular assist devices (LVADs) can successfully bridge children to recovery or transplant. Careful management and appropriate device selection are key for positive outcomes in pediatric LVAD therapy.
Area of Science:
- Pediatric Cardiology
- Cardiovascular Surgery
- Biomedical Engineering
Background:
- Left ventricular assist devices (LVADs) are crucial for managing pediatric heart failure.
- Appropriate device selection and management are vital for successful pediatric LVAD implantation.
Observation:
- A retrospective study reviewed nine pediatric patients (12 days to 15 years; 2.5-73 kg) receiving LVAD support.
- Devices used included Abiomed BVS 5000 and Biomedicus centrifugal pumps.
- Average support duration was 5 days, with a range of 1-11 days.
Findings:
- Eight of nine patients were successfully weaned from LVAD support.
- Four patients underwent heart transplantation, with four discharged as long-term survivors.
- Neurologic sequelae were the most common complication, affecting four patients.
Implications:
- Current LVADs can be effectively used in pediatric patients for bridging to recovery or transplantation.
- Size limitations of existing devices pose challenges for pediatric application.
- Development of new, pediatric-specific LVADs is needed to optimize flow and size characteristics.