Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A nitric oxide sensor using reduction current

W Xu1, S J Yao, S K Wolfson

  • 1Department of Surgery, University of Pittsburgh, Pennsylvania 15219, USA.

ASAIO Journal (American Society for Artificial Internal Organs : 1992)
|July 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

An improved procedure for production of human epidermal growth factor from recombinant E. coli.

Applied microbiology and biotechnology·2002
Same author

Novel benzofuran and benzothiophene biphenyls as inhibitors of protein tyrosine phosphatase 1B with antihyperglycemic properties.

Journal of medicinal chemistry·2001
Same author

The reduced expression of surrogate light chains in B cell precursors from senescent BALB/c mice is associated with decreased E2A proteins.

Mechanisms of ageing and development·2000
Same author

Calreticulin modulates capacitative Ca2+ influx by controlling the extent of inositol 1,4,5-trisphosphate-induced Ca2+ store depletion.

The Journal of biological chemistry·2000
Same author

Ultrafast primary processes in PS I from Synechocystis sp. PCC 6803: roles of P700 and A(0).

Biophysical journal·2000
Same author

Protein kinase C activation contributes to microvascular barrier dysfunction in the heart at early stages of diabetes.

Circulation research·2000
Same journal

Case Series of Extracorporeal Cardiopulmonary Resuscitation for Refractory Cardiopulmonary Arrest After Cardiac Surgery.

ASAIO journal (American Society for Artificial Internal Organs : 1992)·2026
Same journal

Association Between Veno-Venous Extracorporeal Membrane Oxygenation and Right Ventricular Dysfunction in Acute Respiratory Distress Syndrome Patients: A Multicenter Retrospective Propensity-Matched Study.

ASAIO journal (American Society for Artificial Internal Organs : 1992)·2026
Same journal

Prolonged Mechanical Circulatory Support of Neonatal Biventricular Failure via Single Ventricle Conversion With Ventricular Assist Device.

ASAIO journal (American Society for Artificial Internal Organs : 1992)·2026
Same journal

Redefining Limits: Extracorporeal Cardiopulmonary Resuscitation in Adult Thrombotic Thrombocytopenic Purpura.

ASAIO journal (American Society for Artificial Internal Organs : 1992)·2026
Same journal

Blood Coagulation Analysis in Pediatric Patients on Extracorporeal Life Support with Small-Volume Acoustic Tweezing Thromboelastometry.

ASAIO journal (American Society for Artificial Internal Organs : 1992)·2026
Same journal

Intraoperative Surface Echocardiography for Donor Heart Assessment During Normothermic Regional Perfusion.

ASAIO journal (American Society for Artificial Internal Organs : 1992)·2026
See all related articles

A novel electrochemical sensor offers sensitive, rapid, and interference-resistant detection of nitric oxide (NO). This new method improves upon existing techniques for measuring biologically active NO.

Area of Science:

  • Biomedical Engineering
  • Electrochemistry
  • Analytical Chemistry

Background:

  • Nitric oxide (NO) plays a crucial role in various biological processes.
  • Current methods for detecting biologically derived NO are often indirect, time-interval based, and lack continuous monitoring capabilities.
  • Existing direct electrochemical methods for NO detection suffer from significant interference issues.

Purpose of the Study:

  • To develop and present a novel electrochemical sensing method and sensor design for direct and continuous nitric oxide (NO) detection.
  • To overcome the limitations of existing NO detection techniques, including interference and indirect measurement.

Main Methods:

  • A new electrochemical sensor design featuring a hydrophobic membrane-covered tip and an internal electrolyte.

Related Experiment Videos

  • Utilization of platinum working and counter electrodes, and a silver/silver bromide reference electrode.
  • An integrated pulsed amperometric method to facilitate NO redox reactions and measure reduction current.

    • Main Results:

    • The developed NO sensor demonstrates high sensitivity.
    • The sensor exhibits a rapid response time to nitric oxide.
    • The new method shows reduced interference compared to existing electrochemical techniques.

    Conclusions:

    • The novel electrochemical sensor provides a significant advancement for direct and continuous NO detection.
    • This technology addresses the need for improved NO measurement in scientific research.
    • The sensor's sensitivity, rapid response, and low interference make it a valuable tool for studying NO's biological activity.