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Updated: Sep 9, 2026

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
Published on: May 21, 2017
Valve replacement for acute left heart endocarditis
O Detry1, J O Defraigne, R Limet
1Department of Cardiovascular Surgery, University Hospital of Liège, Centre Hospitalier Universitaire de Liege, Domaine Universitaire du Sart-Tilman, Belgium.
Insights
Early valve replacement surgery for acute infective endocarditis offers good survival rates. This study highlights the effectiveness of surgical intervention in managing complicated cases, with low recurrence.
Area of Science:
- Cardiology
- Infectious Diseases
- Cardiac Surgery
Background:
- Infective endocarditis (IE) is a serious infection affecting heart valves.
- Valve replacement is often necessary for IE management, especially in complicated cases.
Purpose of the Study:
- To evaluate the outcomes of valve replacement surgery for acute infective endocarditis.
- To assess the efficacy and safety of early surgical intervention in IE patients.
Main Methods:
- Retrospective analysis of 66 patients undergoing valve replacement for acute IE between 1982 and 1993.
- Data collected on patient demographics, valve involvement, causative organisms, surgical indications, and follow-up outcomes.
- Perioperative mortality, survival rates, and reoperation rates were analyzed.
Main Results:
- Aortic valve (45) and mitral valve (17) were most commonly affected.
- Staphylococci and Streptococci spp. were the primary pathogens (68%).
- Refractory congestive heart failure was the main surgical indication (86%); perioperative mortality was 6%; 1-year and 3-year survival rates were 88.5% and 83%, respectively; 9% required reoperation.
Conclusions:
- Early surgical management of complicated infective endocarditis yields satisfactory results.
- Valve replacement is a viable option for IE, associated with good long-term survival and low recurrence rates.
Abstract:
Between January 1982 and June 1993, 66 patients (48 men and 18 women of mean (range) age 50 (21-77) years) underwent valve replacement for acute infective endocarditis. There were 45 aortic valve and 17 mitral valve infections. Four patients had bivalvular involvement. Fifty-three patients suffered from native valve endocarditis, with underlying valvular lesions documented for 31 patients. Staphylococci and Streptococci spp. were responsible for 68% of infection, and 20% of blood and valve cultures were negative. Refractory congestive heart failure was the leading surgical indication in 86% of patients. The mean follow-up period was 44 months. The perioperative mortality rate was 6%. Actuarial survival rates were 88.5% at 1 year and 83% at 3 years. No early recurrence of infection was noted. Six patients (9%) needed reoperation. Satisfactory results confirm that early surgical management should be considered in patients with complicated infective endocarditis.
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