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Helicobacter pylori infection and chronological extension of atrophic gastritis
K Satoh1, K Kimura, P Sipponen
1Department of Gastroenterology, Jichi Medical School, Tochigi, Japan.
Objectives:
To determine the relationship between Helicobacter pylori infection and chronological extension of atrophic gastritis.
Patients And Methods:
We studied 137 non-ulcer patients. The extent of atrophic gastritis was assessed endoscopically and scored on a scale of 1-6 (endoscopic score) using the atrophic pattern system. H. pylori infection was assessed by enzyme-linked immunosorbent assay with serum anti-H. pylori immunoglobulin G. The correlation between patient age and endoscopic score was determined for H. pylori-positive and -negative patients.
Results:
A positive correlation between age and extent of atrophic gastritis was found in both H. pylori-positive and -negative patients. In groups of patients aged 20-29 and 30-39 years, those with H. pylori had more extensive atrophic gastritis than those without H. pylori.
Conclusions:
Chronological extension of atrophic gastritis was found in patients with and without H. pylori infection.