Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Mal de Meleda

F Urbina1, M C Cristóbal, R Sandoval

  • 1Caja de Previsión de la Defensa Nacional, Santiago, Chile.

Cutis
|October 1, 1995
PubMed
Summary
This summary is machine-generated.

This report details a rare case of mal de Meleda in Chile, a progressive palmoplantar keratoderma. The condition presented with widespread hyperkeratotic plaques, unaffected by family history or consanguinity.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Age of Onset of Psoriasis is Significantly Lower in Girls in Spain.

Actas dermo-sifiliograficas·2026
Same author

Neutron imaging of the deuterium-tritium tamping gas volume in an inertial confinement fusion hohlraum.

The Review of scientific instruments·2024
Same author

Frequency dynamics of a chain of magnetized rotors: dumbbell model vs Landau-Lifshitz equation.

Journal of physics. Condensed matter : an Institute of Physics journal·2022
Same author

Effectiveness of egg yolk immunoglobulin against the intracellular salmonid pathogen Piscirickettsia salmonis.

Journal of applied microbiology·2015
Same author

Circumscribed palmar or plantar hypokeratosis 10 years after the first description: what is known and the issues under discussion.

Actas dermo-sifiliograficas·2013
Same author

Pigmented fungiform papillae of the tongue in Laugier disease (or Laugier-Hunziker syndrome).

Actas dermo-sifiliograficas·2012
Same journal

Black Dots on the Scalp of a Child.

Cutis·2026
Same journal

Psoriasis and Obesity: A Clinical Review of the Bidirectional Link and Management Implications.

Cutis·2026
Same journal

Adalimumab in Lichen Planus: A Narrative Review of Treatment and Paradoxical Reactions.

Cutis·2026
Same journal

The Future of Psoriasis Care.

Cutis·2026
Same journal

Evaluating GPT-4o for Automated Classification of Skin Lesions Using the HAM10000 Dataset.

Cutis·2026
Same journal

Metastatic Primary Extramammary Paget Disease: A Case Series.

Cutis·2026
See all related articles

Area of Science:

  • Dermatology
  • Medical Genetics

Background:

  • Mal de Meleda is a rare autosomal recessive disorder characterized by progressive palmoplantar keratoderma.
  • Understanding its genetic basis and clinical manifestations is crucial for diagnosis and management.

Observation:

  • A unique case of mal de Meleda was identified in Chile.
  • The patient exhibited no consanguinity and no family history of the condition across four generations.

Findings:

  • The patient presented with progrediens and transgrediens palmoplantar keratoderma.
  • Additional hyperkeratotic plaques were observed on the knees and elbows.
  • Nails, hair, and teeth remained unaffected, differentiating it from other genodermatoses.

Implications:

Related Experiment Videos

  • This case expands the geographical understanding of mal de Meleda.
  • Further research into potential novel genetic mutations or environmental factors may be warranted.
  • Highlights the importance of thorough clinical examination for diagnosing rare dermatological conditions.