Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Recurrent thymoma: evidence for histological progression

E Pescarmona1, E A Rendina, F Venuta

  • 1Department of Experimental Medicine and Pathology, University La Sapienza, Rome, Italy.

Histopathology
|November 1, 1995
PubMed
Summary

Recurrent thymomas with cortical differentiation show histological progression and aggressive behavior, leading to poor patient outcomes. Careful follow-up is crucial for all thymoma types, even those initially appearing non-invasive.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Expression of TCL1 and CD27 in primary cutaneous B-cell lymphomas.

Histopathology·2006
Same author

[The Haemolymphopathology Italian Group (H.I.G.): an essential resource for the new technical and organization problems troubling modern haemolymphopathology diagnostics].

Pathologica·2006
Same author

Nodal peripheral T-cell lymphoma associated with Warthin's tumour.

Histopathology·2005
Same author

[The thymus gland of rhesus macaque in SIV vaccination/infection].

Pathologica·2004
Same author

A rapid, low-dose, 13C-urea tablet for the detection of Helicobacter pylori infection before and after treatment.

Alimentary pharmacology & therapeutics·2003
Same author

Phage display and colony filter screening for high-throughput selection of antibody libraries.

Combinatorial chemistry & high throughput screening·2002

Area of Science:

  • Oncology
  • Pathology

Background:

  • Investigated clinicopathological features of nine recurrent thymoma cases.
  • Focused on thymomas with cortical differentiation.

Observation:

  • All initial cases classified as thymomas with cortical differentiation.
  • Five cases showed histological progression to more advanced types upon recurrence.
  • Recurrence associated with more advanced clinical stage.

Findings:

  • Thymomas with cortical differentiation are related neoplasms with aggressive behavior and high recurrence risk.
  • Recurrent thymomas in this series had a poor prognosis, with 66.6% mortality.
  • Histological progression observed from predominantly cortical thymoma to cortical thymoma and/or thymic carcinoma.

Related Experiment Videos

Implications:

  • Thymomas with cortical differentiation require vigilant, long-term patient monitoring.
  • Even non-invasive thymomas necessitate careful follow-up due to recurrence potential.
  • Findings highlight the aggressive nature and relatedness of thymoma subtypes with cortical differentiation.