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Related Experiment Videos

Cervical cord atrophy--a pattern of presentation

M Direkze, B G Parsons-Smith

    Acta Neurologica Scandinavica
    |April 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

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    This study describes a rare neurological condition, veno-occlusive disease of the upper cervical cord, observed in seven patients. The condition presented with a distinct pattern of limb weakness and hand muscle wasting.

    Area of Science:

    • Neurology
    • Vascular Neurology
    • Spinal Cord Medicine

    Background:

    • Veno-occlusive disease (VOD) typically affects the liver, but this study explores its manifestation in the central nervous system.
    • Understanding rare spinal cord vascular pathologies is crucial for accurate diagnosis and treatment.

    Observation:

    • Seven patients presented with a unique sequential pattern of limb weakness, starting in one upper limb and progressing contralaterally.
    • All patients exhibited hand muscle wasting indicative of a lower motor neuron lesion at the C8 spinal cord segment.
    • Tumors at the foramen magnum were ruled out in all cases.

    Findings:

    • The clinical presentation suggests a specific pattern of spinal cord ischemia due to veno-occlusive disease.
    • The C8 spinal cord segment appears particularly vulnerable in this condition.

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  • The observed neurological deficits are consistent with vascular compromise in the upper cervical cord.

    • Implications:

    • This case series introduces and defines a novel clinical entity: veno-occlusive disease of the upper cervical cord.
    • Early recognition of this distinct pattern of limb weakness can aid in diagnosing this rare spinal vascular disorder.
    • Further research into the pathophysiology and treatment of spinal cord VOD is warranted.