Subcellular distribution of oxygen free radical scavenging enzymes in goat ovary

Oxygen free radical scavenging enzymes superoxide dismutase (SOD), peroxidase (POD) and catalase were heterogeneously distributed in goat ovary. Activities of SOD and catalase were predominantly located in cytosolic fractions compared to mitochondrial and microsomal fractions. Most of the peroxidase activity was observed in microsomal fractions with little activity in cytosolic and mitochondrial fractions. Higher activities of all these enzymes were in luteal phase as compared to follicular phase. Most of the activities of these enzymes in luteal phase were restricted to luteal cells while in follicular phase these were mainly present in the follicles of the ovary.