Related Experiment Videos
MRI in predicting the response of ovarian endometriomas to hormone therapy
K Sugimura1, H Okizuka, Y Kaji
1Department of Radiology, Shimane Medical University, Izumo, Japan.
Objective:
Our goal was to investigate the usefulness of MRI in predicting the response of endometriomas to hormone therapy.
Materials And Methods:
MRI and laparoscopy at the onset of treatment and follow-up MRI after 6 months of hormone therapy were performed in 21 patients with 49 endometriomas. T1- and T2-weighted images were obtained with a 1.5 T apparatus using a body coil. The lesions were divided into a responder group and a nonresponder group according to whether the lesion size decreased by > or = 50% or not.
Results:
With MRI, shading was seen in 25 of 27 lesions (93%) from the nonresponder group, but in only 6 of 22 (27%) from the responder group. Low SI rim was seen in 59% of the responders and 89% of the nonresponders. Multiplicity in 68% of the responders and in 85% of the nonresponders and irregularity in 41% of the responders and in 78% of the nonresponders were shown. Multiple logistic analysis revealed shading was the most important factor in prediction of the response to hormone therapy.
Conclusion:
Shading was an important sign in evaluating the response of endometriomas to hormone therapy. MRI may assist in selecting the appropriate therapy for endometriomas.