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Acute focal bacterial nephritis in childhood brucellosis
N Loberant1, V Salamon, J Jerushalmi
1Department of Radiology, Western Galilee Regional Hospital, Nahariya, Israel.
Abstract:
Brucellosis is an infectious disease transmitted from various animal hosts to man. In children the most common route of infection is unpasteurized milk or milk products. Brucellosis affects the urinary tract uncommonly, most frequently causing orchioepididymitis. We report the case of a 4-year-old boy with brucellosis who developed acute focal bacterial nephritis (AFBN), documented by sonography, gallium scan, and computed tomography. After appropriate treatment his symptoms and his sonographic abnormality resolved completely. To the best of our knowledge, this is the first report of the association of AFBN and brucellosis.
Insights
Brucellosis, an animal-to-human infection, uncommonly affects the urinary tract. This case study details a child with brucellosis who developed acute focal bacterial nephritis (AFBN), a rare complication.
Area of Science:
- Infectious Diseases
- Pediatrics
- Nephrology
Background:
- Brucellosis is a zoonotic infection with diverse clinical presentations.
- Urinary tract involvement in pediatric brucellosis is infrequent, typically manifesting as orchioepididymitis.
- Acute focal bacterial nephritis (AFBN) is a rare renal complication of bacterial infections.
Observation:
- A 4-year-old boy presented with brucellosis.
- The patient developed AFBN, a rare complication of brucellosis.
- Diagnostic imaging included sonography, gallium scan, and computed tomography.
Findings:
- Brucellosis was confirmed as the cause of AFBN in this pediatric patient.
- Imaging studies successfully documented the presence and extent of AFBN.
- Complete resolution of symptoms and imaging abnormalities was achieved after treatment.
Implications:
- This case highlights a previously unreported association between brucellosis and AFBN in children.
- Early diagnosis and treatment of brucellosis may prevent or manage renal complications.
- Further research is warranted to understand the pathophysiology and incidence of AFBN in pediatric brucellosis.