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Eosinophilic gastroenteritis

M Lee1, W G Hodges, T L Huggins

  • 1Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, USA.

Southern Medical Journal
|February 1, 1996
PubMed
Summary
This summary is machine-generated.

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Eosinophilic gastroenteritis is a rare gastrointestinal disorder marked by eosinophil buildup. Treatment varies from observation for mild cases to corticosteroids or surgery for severe symptoms.

Area of Science:

  • Gastroenterology
  • Immunology

Background:

  • Eosinophilic gastroenteritis is a rare condition of unknown cause.
  • It involves peripheral eosinophilia and eosinophilic infiltration of the GI tract.

Observation:

  • Classified by the affected GI layer: mucosal, muscular, or subserosal.
  • Symptoms range from abdominal pain and diarrhea to obstructive symptoms and ascites.

Findings:

  • Mild symptoms may be managed with observation.
  • Disabling symptoms often respond to corticosteroids after excluding other disorders.
  • Allergic history may guide treatment with sodium cromolyn, ketotifen, or diets.

Implications:

  • Early diagnosis and classification are key to effective management.

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  • Corticosteroids are a primary treatment for severe eosinophilic gastroenteritis.
  • Surgery may be necessary for complications like obstruction or refractory disease.