Related Experiment Video
Updated: Aug 2, 2026

Ex Vivo Imaging of Postnatal Cerebellar Granule Cell Migration Using Confocal Macroscopy
Published on: May 12, 2015
Cellular receptors in the regulation of plasmin generation
1Department of Pediatrics, Cornell University Medical College of New York, New York 10021, USA.
Abstract:
Cell surface receptors may play a significant role in the regulation of plasmin generation. Although structurally diverse, these receptors can be classified on a functional basis into two groups. Activation receptors for plasminogen and plasminogen activators serve to localize, and in some cases, potentiate plasminogen activation, and are expressed on endothelial cells, blood cells, neuronal cells, and tumor cells. Clearance receptors, on the other hand, serve to eliminate plasmin and plasminogen activators from blood or focal micro-environments. They are found primarily on parenchymal hepatocytes and tissue macrophages. It is likely that integrated actions of both classes of receptors are essential to the homeostatic control of plasmin activity. Knowledge of how these receptors themselves are regulated may provide an important key to understanding a host of biologic processes.
More Related Videos
10:59Conditional Knockdown of Gene Expression in Cancer Cell Lines to Study the Recruitment of Monocytes/Macrophages to the Tumor Microenvironment
Published on: November 23, 2017
07:13Characterizing Modulators of Protease-Activated Receptors with a Calcium Mobilization Assay Using a Plate Reader
Published on: May 24, 2024
Related Concept Videos
Cytoskeletal Linker Proteins - Plakins
Amplifying Signals via Enzymatic Cascade
GPCR Desensitization
Intracellular Signaling Affects Focal Adhesions
Some...
Transducer Mechanism: Enzyme-Linked Receptors
Major types that are helpful drug targets include:
Clot Retraction and Fibrinolysis