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Neuronal ceroid-lipofuscinosis in a cat
R Bildfell1, C Matwichuk, S Mitchell
1Department of Pathology and Microbiology, Atlantic Veterinary College, University of Prince Edward Island, Canada.
Veterinary Pathology
|September 1, 1995
Summary
Neuronal ceroid-lipofuscinosis, a rare neurological disorder, was diagnosed in a cat presenting with blindness and seizures. Pigment accumulation was confined to neural tissues, differing from human cases.
Area of Science:
- Veterinary Neurology
- Cellular Pathology
Background:
- Neuronal ceroid-lipofuscinoses (NCLs) are a group of inherited metabolic disorders.
- These lysosomal storage diseases are characterized by the accumulation of autofluorescent ceroid-lipofuscin pigment within cells.
- NCLs affect both humans and animals, leading to progressive neurodegeneration.